James Cookの45ヤードTDランでBillsが先制したが、Texansは第2QにDavis MillsからChristian Kirk、Jayden HigginsへTDを通し、Ray Davisの97ヤードキックオフリターンTDも挟む打ち合いを経て20-16とリードして折り返した。
第3Q終了間際のKa'imi FairbairnのFGで23-16とすると、第4QはBuffaloがMatt PraterのFGで19-23と1ポゼッション差に迫る。しかし残り24秒、Calen BullockがJosh Allenからインターセプトを奪い、反撃を断ち切った。Millsは153ヤード2TD (0INT)。BuffaloはAllenが2INTを喫し、総ヤードで326対261と上回りながら3つのターンオーバーが響いて19点止まり。Houstonが23-19で競り勝った。
2インターセプトと1フォースファンブルでBuffaloの攻撃を再三止めた守備の中心。総ヤードで上回られながら、残り24秒のインターセプトで最後の反撃を断ち、3点差の逃げ切りを決めた。
(Shotgun) J.Allen pass short left intended for J.Palmer INTERCEPTED by C.Bullock at HOU 9. C.Bullock to HOU 9 for no gain (J.Palmer). Penalty on G.Davis, Offensive Pass Interference, declined. Drive-ending interception. Score after play: BUF 19, HOU 23.
K.Fairbairn kicks 62 yards from HOU 35 to BUF 3. R.Davis for 97 yards, TOUCHDOWN. Touchdown swings the leverage immediately. Score after play: BUF 16, HOU 13.
J.Cook right tackle for 45 yards, TOUCHDOWN. Touchdown swings the leverage immediately. Score after play: BUF 6, HOU 0.
(Shotgun) D.Mills pass short left to J.Higgins for 8 yards, TOUCHDOWN. Injury Update: N.Collins has returned to the game. Penalty on C.Lewis, Defensive Pass Interference, declined. Touchdown swings the leverage immediately. Score after play: BUF 16, HOU 20.
(Shotgun) J.Allen pass short left to K.Shakir to BUF 28 for 13 yards (C.Bullock). FUMBLES (C.Bullock), RECOVERED by J.Reed at BUF 31. J.Reed to BUF 22 for 9 yards (D.Knox). Turnover flips the possession. Score after play: BUF 16, HOU 20.